Detalhe da pesquisa
1.
Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.
Cell
; 183(1): 258-268.e12, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32860739
2.
Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents.
Proc Natl Acad Sci U S A
; 118(3)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33402433
3.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature
; 538(7625): 344-349, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602946
4.
Control of inflammation by stromal Hedgehog pathway activation restrains colitis.
Proc Natl Acad Sci U S A
; 113(47): E7545-E7553, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27815529
5.
Conformation-guided analogue design identifies potential antimalarial compounds through inhibition of mitochondrial respiration.
Org Biomol Chem
; 16(30): 5403-5406, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30009295
6.
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Br J Pharmacol
; 180(15): 1899-1929, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37197802
7.
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance.
Cell Chem Biol
; 29(5): 824-839.e6, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233174
8.
Bicyclic Imidazolium Inhibitors of Gli Transcription Factor Activity.
ChemMedChem
; 15(12): 1044-1049, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32268014
9.
In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model.
Sci Transl Med
; 11(521)2019 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31801884
10.
Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum.
ACS Infect Dis
; 4(4): 508-515, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29336544
11.
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
Science
; 362(6419)2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30523084
12.
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.
Science
; 359(6372): 191-199, 2018 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326268
13.
A Novel Methodology for Bioenergetic Analysis of Plasmodium falciparum Reveals a Glucose-Regulated Metabolic Shift and Enables Mode of Action Analyses of Mitochondrial Inhibitors.
ACS Infect Dis
; 2(12): 903-916, 2016 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27718558
14.
Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.
ACS Chem Biol
; 11(1): 53-60, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26555042
15.
A broad analysis of resistance development in the malaria parasite.
Nat Commun
; 7: 11901, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27301419